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Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design

The cyclotide family of plant proteins is of interest because of their unique topology, which combines a head-to-tail cyclic backbone with an embedded cystine knot, and because their remarkable chemical and biological properties make them ideal candidates as grafting templates for biologically activ...

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Bibliografiske detaljer
Main Authors: Clark, Richard J., Daly, Norelle L., Craik, David J.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1386006/
https://ncbi.nlm.nih.gov/pubmed/16300479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051691
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