Adoptive T cell therapy using antigen-specific CD8(+) T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells

Adoptive T cell therapy, involving the ex vivo selection and expansion of antigen-specific T cell clones, provides a means of augmenting antigen-specific immunity without the in vivo constraints that can accompany vaccine-based strategies. A phase I study was performed to evaluate the safety, in viv...

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发表在:	Proc Natl Acad Sci U S A
Principais autores:	Yee, C., Thompson, J. A., Byrd, D., Riddell, S. R., Roche, P., Celis, E., Greenberg, P. D.
格式:	Artigo
语言:	Inglês
出版:	National Academy of Sciences 2002
主题:	Biological Sciences
在线阅读:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC138583/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12427970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242600099
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