Blockade of CD73 Increases the Cytotoxic Effects of Fludarabine in Chronic Lymphocytic Leukemia
Background: Ecto-5’-nucleotidase (CD73) is a membrane-bound enzyme that converts adenosine 5’-monophosphate into adenosine. It is proven that the presence of elevated levels of adenosine in the tumor microenvironment induces tumor growth while suppressing immune responses against tumor cells. Accord...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tabriz University of Medical Sciences
2022-12-01
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| Colecção: | ImmunoAnalysis |
| Assuntos: | |
| Acesso em linha: | https://ia.tbzmed.ac.ir/PDF/ia-2-11.pdf |
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