Blockade of CD73 Increases the Cytotoxic Effects of Fludarabine in Chronic Lymphocytic Leukemia

Background: Ecto-5’-nucleotidase (CD73) is a membrane-bound enzyme that converts adenosine 5’-monophosphate into adenosine. It is proven that the presence of elevated levels of adenosine in the tumor microenvironment induces tumor growth while suppressing immune responses against tumor cells. Accord...

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Библиографические подробности

Главные авторы:	Mohammad Sadeghi, Mahsa Yousefi Bostanabad, Omid Abedi, Abbas Ali Hosseinpour Feizi, Ali Akbar Movasaghpour Akbari, Farhad Jadidi-Niaragh
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Tabriz University of Medical Sciences 2022-12-01
Серии:	ImmunoAnalysis
Предметы:	cll fludarabine cd73 leukemia sirna chemoresistance
Online-ссылка:	https://ia.tbzmed.ac.ir/PDF/ia-2-11.pdf
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