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Coordination of kinesin's two heads studied with mutant heterodimers
A conventional kinesin molecule has two identical catalytic domains (heads) and is thought to use them alternately to move processively, with 8-nm steps. To clarify how each head contributes to the observed steps, we have constructed heterodimeric kinesins that consist of two distinct heads. The het...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC138564/ https://ncbi.nlm.nih.gov/pubmed/12451178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.252409199 |
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