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Experimental treatment of autoimmune MRL-lpr/lpr mice with immunosuppressive compound FK506.
A newly developed immunosuppressive drug, FK506 (Fujisawa, Japan) is known to inhibit T-cell immunity. We have evaluated the action of this compound in MRL/lpr mice which develop a severe autoimmune disease. Eight-week-old female MRL/lpr of mice were treated subcutaneously with 2 mg/kg (high dose),...
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Główni autorzy: | , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
1990
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1385593/ https://ncbi.nlm.nih.gov/pubmed/1689694 |
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