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Experimental treatment of autoimmune MRL-lpr/lpr mice with immunosuppressive compound FK506.

A newly developed immunosuppressive drug, FK506 (Fujisawa, Japan) is known to inhibit T-cell immunity. We have evaluated the action of this compound in MRL/lpr mice which develop a severe autoimmune disease. Eight-week-old female MRL/lpr of mice were treated subcutaneously with 2 mg/kg (high dose),...

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Main Authors: Yamamoto, K, Mori, A, Nakahama, T, Ito, M, Okudaira, H, Miyamoto, T
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1990
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385593/
https://ncbi.nlm.nih.gov/pubmed/1689694
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