Crystal structure of a DNA decamer containing a cis-syn thymine dimer

It is well known that exposure to UV induces DNA damage, which is the first step in mutagenesis and a major cause of skin cancer. Among a variety of photoproducts, cyclobutane-type pyrimidine photodimers (CPD) are the most abundant primary lesion. Despite its biological importance, the precise relat...

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Bibliographic Details
Main Authors: Park, HaJeung, Zhang, Kaijiang, Ren, Yingjie, Nadji, Sourena, Sinha, Nanda, Taylor, John-Stephen, Kang, ChulHee
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC138548/
https://ncbi.nlm.nih.gov/pubmed/12456887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.242422699
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