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Inhibition of murine B-lymphocyte proliferation by the novel immunosuppressive drug FK-506.

The novel immunosuppressive drug FK-506 inhibits both cell-mediated and humoral immunity in vivo and suppresses T-lymphocyte activation at nanamolar concentrations in vitro. We report here that FK-506 also inhibits the in vitro proliferation of murine B lymphocytes induced by goat antimouse IgM (GaM...

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Detalhes bibliográficos
Main Authors: Walliser, P, Benzie, C R, Kay, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385461/
https://ncbi.nlm.nih.gov/pubmed/2480331
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