Human thyroglobulin autoantibodies of subclasses IgG2 and IgG4 bind to different epitopes on thyroglobulin.

IgG autoantibodies to thyroglobulin (Tg) in the serum of patients with autoimmune thyroid disease only recognize a very limited number of epitopes, probably between four and six (Nye, Pontes De Carvalho & Roitt, 1980) on the large Tg molecule (660,000 MW), but attempts to characterize the epitop...

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Main Authors: Fukuma, N, McLachlan, S M, Petersen, V B, Kau, P, Bradbury, J, Devey, M, Bleasdale, K, Grabowski, P, Smith, B R
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385301/
https://ncbi.nlm.nih.gov/pubmed/2472355
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