Thyroglobulin autoantibodies switch to immunoglobulin (Ig)G1 and IgG3 subclasses and preserve their restricted epitope pattern after (131)I treatment for Graves' hyperthyroidism: the activity of autoimmune disease influences subclass distribution but not epitope pattern of autoantibodies

The subclass distribution of thyroglobulin autoantibodies (TgAb) is debated, whereas their epitope pattern is restricted. Radioidine ((131)I) treatment for Graves' disease (GD) induces a rise in TgAb levels, but it is unknown whether it modifies subclass distribution and epitope pattern of TgAb...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Latrofa, F, Ricci, D, Montanelli, L, Piaggi, P, Mazzi, B, Bianchi, F, Brozzi, F, Santini, P, Fiore, E, Marinò, M, Tonacchera, M, Vitti, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238871/
https://ncbi.nlm.nih.gov/pubmed/25134846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12438
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