Spleen lymphocyte populations and expression of activation markers in rats treated with the potent new immunosuppressive agent FK-506.

Rats were immunized systemically with sheep red blood cells (SRBC) and treated with either FK-506 (1 mg/kg/day) or cyclosporin A (CsA) (25 mg/kg/day) for 7 days. Profound (greater than 90%) suppression of the production of splenic IgM-secreting plasma cells and circulating antibody levels was observ...

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Bibliografske podrobnosti
Main Authors: Woo, J, Stephen, M, Thomson, A W
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385035/
https://ncbi.nlm.nih.gov/pubmed/2460401
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