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Antigenicity of the carboxyl terminus of insulin: isolation of human insulin-specific monoclonal antibodies.

Monoclonal technology was used to isolate antibodies binding the B30 (carboxy) terminal residue in the polyclonal-provoked immune response to human insulin. Although both spleen and lymph node cell fusions were carried out, only the latter were successful in isolating monoclonal antibodies that boun...

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Autors principals: Mirza, I H, Wilkin, T J
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385017/
https://ncbi.nlm.nih.gov/pubmed/3053426
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