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Transcriptional and post-transcriptional mechanisms involved in the differential expression of LPS-induced IL-1 and TNF mRNA.

The amplification of cytokine mRNA following incubation of macrophages with inflammatory stimuli and protein synthesis inhibitors has been related to stabilization of labile mRNA species containing the 3'AUUUA consensus sequence. In the present study, cycloheximide-treated lipopolysaccharide (L...

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Main Authors: Zuckerman, S H, Evans, G F, Guthrie, L
Formato: Artigo
Idioma:Inglês
Publicado: 1991
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384577/
https://ncbi.nlm.nih.gov/pubmed/1916897
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