Identification of amino acids in the V3 region of gp120 critical for virus neutralization by human HIV-1-specific antibodies.

The importance of the dependence on single amino acids in the V3 region of HIV-1 gp120 was evaluated for virus neutralization and antibody-dependent cellular cytotoxicity (ADCC). Synthetic overlapping 15-mer peptides and a set of omission peptides covering amino acids 301-317 were used. Sera from 29...

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Bibliographic Details
Main Authors: Broliden, P A, Mäkitalo, B, Akerblom, L, Rosen, J, Broliden, K, Utter, G, Jondal, M, Norrby, E, Wahren, B
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384562/
https://ncbi.nlm.nih.gov/pubmed/1916888
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