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The effect of transfected MHC class I genes on sensitivity to natural killer cells.

To test the hypothesis that major histocompatibility complex (MHC) molecules protect target cells from lysis by natural killer cells (NKC), we transfected the MHC- B16 melanoma line F10 with the class I genes encoding Dd, Kb, and Kk. Only low levels of Dd expression could be obtained and there was n...

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Detalhes bibliográficos
Main Authors: Holscher, M, Givan, A L, Brooks, C G
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384516/
https://ncbi.nlm.nih.gov/pubmed/1904402
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