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Mechanisms of inhibition of mononuclear cell activation by the iron-chelating agent desferrioxamine.

Iron-withholding by the chelating agent desferrioxamine abrogates the proliferative response of human peripheral blood mononuclear cells (PBMC) to phytohaemagglutinin (PHA). The present study investigated whether desferrioxamine operates late in the activation process or, as recently suggested, at a...

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Autors principals: Polson, R J, Jenkins, R, Lombard, M, Williams, A C, Roberts, S, Nouri-Aria, K, Williams, R, Bomford, A
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384300/
https://ncbi.nlm.nih.gov/pubmed/2228020
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