Specific immunotherapy with tumour-draining lymph node cells cultured with both anti-CD3 and anti-CD28 monoclonal antibodies.

For providing costimulatory signals, we utilized anti-CD28 monoclonal antibody (mAb) for the in vitro culture of tumour-draining lymph node (LN) cells. The proliferation of B16 melanoma-draining LN cells in the culture with anti-CD3 mAb was remarkably enhanced by the addition of anti-CD28 mAb. In cu...

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Detalhes bibliográficos
Main Authors: Harada, M, Okamoto, T, Omoto, K, Tamada, K, Takenoyama, M, Hirashima, C, Ito, O, Kimura, G, Nomoto, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1384115/
https://ncbi.nlm.nih.gov/pubmed/8778032
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