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Antagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantation()

It has been widely presumed that antibody-mediated selective costimulatory molecule blockade of CD28 is superior to CTLA4-Ig. This is based on the premise that specifically blocking CD28 allows inhibitory signals through CTLA-4 to proceed, adding further to the down-regulation of T-cell function. Th...

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Autors principals: Graves, Scott S., Stone, Diane M., Loretz, Carol, Peterson, Laura J., Lesnikova, Marina, Hwang, Billanna, Georges, George E., Nash, Richard, Storb, Rainer
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180996/
https://ncbi.nlm.nih.gov/pubmed/21343872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31820f07ff
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