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Antagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantation()
It has been widely presumed that antibody-mediated selective costimulatory molecule blockade of CD28 is superior to CTLA4-Ig. This is based on the premise that specifically blocking CD28 allows inhibitory signals through CTLA-4 to proceed, adding further to the down-regulation of T-cell function. Th...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180996/ https://ncbi.nlm.nih.gov/pubmed/21343872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31820f07ff |
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