IL-4 is able to reverse the CD2-mediated negative apoptotic signal to CD4-CD8- alpha beta and/or gamma delta T lymphocytes.

Activation of immature thymocytes or transformed T lymphocytes via T-cell receptor (TCR)/CD3 signalling can induce programmed cell death (apoptosis). Recent data indicate that anti-CD3/TCR monoclonal antibodies (mAb) also trigger apoptosis in activated (but not resting) mature peripheral blood T lym...

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Autors principals: Spinozzi, F, Nicoletti, I, Agea, E, Belia, S, Moraca, R, Migliorati, G, Riccardi, C, Grignani, F, Bertotto, A
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383940/
https://ncbi.nlm.nih.gov/pubmed/8550074
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