The effects of changes at peptide residues contacting MHC class II T-cell receptor on antigen recognition and human Th0 cell effector function.

Cytokines can influence the selection of functional subsets (Th1 or Th2) of CD4+ T cells. However, quantitative changes in affinity of peptide/major histocompatibility complex (MHC) class II/T-cell receptor (TCR) interactions may alter antigen density and modulate T-cell effector function. The possi...

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Detalhes bibliográficos
Main Authors: Lamb, J R, Higgins, J A, Hetzel, C, Hayball, J D, Lake, R A, O'Hehir, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383919/
https://ncbi.nlm.nih.gov/pubmed/7558134
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