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Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells

Nkx3.1 is a homeodomain-containing transcription factor that is expressed early in the development of the prostate gland and is believed to play an important role in the differentiation of prostatic epithelia. Loss of Nkx3.1 protein expression is often an early event in prostate tumorigenesis, and t...

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Hlavní autoři: Simmons, Steven O., Horowitz, Jonathan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383699/
https://ncbi.nlm.nih.gov/pubmed/16201967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051030
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