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Interaction with phospholipids modulates α-synuclein nitration and lipid–protein adduct formation
Intracellular aggregates of α-syn (α-synuclein) represent pathoanatomical hallmarks of neurodegenerative disorders (synucleinopathies). The molecular mechanisms underlying α-syn aggregation into filamentous inclusions may involve oxidation and nitration of the protein. Whereas the effects of oxidant...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Portland Press Ltd.
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383693/ https://ncbi.nlm.nih.gov/pubmed/16146428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051277 |
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