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Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome

Current models of the core of the spliceosome include a network of RNA–RNA interactions involving the pre-mRNA and the U2, U5, and U6 snRNAs. The essential spliceosomal protein Prp8 interacts with U5 and U6 snRNAs and with specific pre-mRNA sequences that participate in catalysis. This close associa...

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Detaylı Bibliyografya
Asıl Yazarlar: TURNER, IAN A., NORMAN, CHRISTINE M., CHURCHER, MARK J., NEWMAN, ANDREW J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Copyright 2006 by RNA Society 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383577/
https://ncbi.nlm.nih.gov/pubmed/16431982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2229706
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