Rapid, Diffusional Shuttling of Poly(A) RNA between Nuclear Speckles and the Nucleoplasm

Speckles are nuclear bodies that contain pre-mRNA splicing factors and polyadenylated RNA. Because nuclear poly(A) RNA consists of both mRNA transcripts and nucleus-restricted RNAs, we tested whether poly(A) RNA in speckles is dynamic or rather an immobile, perhaps structural, component. Fluorescein...

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Autori principali: Politz, Joan C. Ritland, Tuft, Richard A., Prasanth, Kannanganattu V., Baudendistel, Nina, Fogarty, Kevin E., Lifshitz, Larry M., Langowski, Jörg, Spector, David L., Pederson, Thoru
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382313/
https://ncbi.nlm.nih.gov/pubmed/16371503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-10-0952
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