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Using Linkage Genome Scans to Improve Power of Association in Genome Scans

Scanning the genome for association between markers and complex diseases typically requires testing hundreds of thousands of genetic polymorphisms. Testing such a large number of hypotheses exacerbates the trade-off between power to detect meaningful associations and the chance of making false disco...

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Autori principali: Roeder, Kathryn, Bacanu, Silvi-Alin, Wasserman, Larry, Devlin, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380233/
https://ncbi.nlm.nih.gov/pubmed/16400608
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