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Genome-Wide Significance Levels and Weighted Hypothesis Testing
Genetic investigations often involve the testing of vast numbers of related hypotheses simultaneously. To control the overall error rate, a substantial penalty is required, making it difficult to detect signals of moderate strength. To improve the power in this setting, a number of authors have cons...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920568/ https://ncbi.nlm.nih.gov/pubmed/20711421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/09-STS289 |
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