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Variants Associated with Common Disease Are Not Unusually Differentiated in Frequency across Populations

Genetic variants that contribute to risk of common disease may differ in frequency across populations more than random variants in the genome do, perhaps because they have been exposed to population-specific natural selection. To assess this hypothesis empirically, we analyzed data from two groups o...

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Autores principales: Lohmueller, Kirk E., Mauney, Matthew M., Reich, David, Braverman, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society of Human Genetics 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380210/
https://ncbi.nlm.nih.gov/pubmed/16385456
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