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Functional Variant in a Bitter-Taste Receptor (hTAS2R16) Influences Risk of Alcohol Dependence

A coding single-nucleotide polymorphism (cSNP), K172N, in hTAS2R16, a gene encoding a taste receptor for bitter β-glucopyranosides, shows significant association with alcohol dependence (P=.00018). This gene is located on chromosome 7q in a region reported elsewhere to exhibit linkage with alcohol d...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hinrichs, Anthony L., Wang, Jen C., Bufe, Bernd, Kwon, Jennifer M., Budde, John, Allen, Rebecca, Bertelsen, Sarah, Evans, Whitney, Dick, Danielle, Rice, John, Foroud, Tatiana, Nurnberger, John, Tischfield, Jay A., Kuperman, Samuel, Crowe, Raymond, Hesselbrock, Victor, Schuckit, Marc, Almasy, Laura, Porjesz, Bernice, Edenberg, Howard J., Begleiter, Henri, Meyerhof, Wolfgang, Bierut, Laura J., Goate, Alison M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Human Genetics 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380207/
https://ncbi.nlm.nih.gov/pubmed/16385453
Tagiau: Ychwanegu Tag
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