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Influence of nicardipine on the pharmacokinetics and pharmacodynamics of propranolol in healthy volunteers.

1. The influence of a single oral dose of nicardipine 30 mg on the pharmacokinetics and pharmacodynamics of propranolol 80 mg was investigated in twelve healthy volunteers. 2. Co-administration of nicardipine significantly increased the AUC and the mean Cmax of propranolol. 3. Blood pressure and hea...

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Autors principals: Schoors, D F, Vercruysse, I, Musch, G, Massart, D L, Dupont, A G
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380147/
https://ncbi.nlm.nih.gov/pubmed/2350528
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