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The contribution of nisoldipine-induced changes in liver blood flow to its pharmacokinetics after oral administration.

1. The pharmacokinetics of nisoldipine (10 mg) was assessed in 10 healthy subjects after single dose and multiple dose oral administration. Apparent liver blood flow was measured, using ICG before and during the absorption phase of nisoldipine. 2. Apparent liver blood flow was increased both on acut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van Harten, J, Burggraaf, J, Danhof, M, van Brummelen, P, Breimer, D D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1379923/
https://ncbi.nlm.nih.gov/pubmed/2757881
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