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Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice

The kinesin superfamily proteins (KIFs) play essential roles in receptor transportation along the microtubules. KIF17 transports the N-methyl-d-aspartate receptor NR2B subunit in vitro, but its role in vivo is unknown. To clarify this role, we generated transgenic mice overexpressing KIF17 tagged wi...

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Detalhes bibliográficos
Main Authors: Wong, Richard Wing-Chuen, Setou, Mitsutoshi, Teng, Junlin, Takei, Yosuke, Hirokawa, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137912/
https://ncbi.nlm.nih.gov/pubmed/12391294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222371099
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