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A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones

RIMs are presynaptic active zone proteins that regulate neurotransmitter release. We describe two related genes that encode proteins with identical C-terminal sequences that bind to the conserved PDZ domain of RIMs via an unusual PDZ-binding motif. These proteins were previously reported separately...

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Autores principales: Wang, Yun, Liu, Xinran, Biederer, Thomas, Südhof, Thomas C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC137906/
https://ncbi.nlm.nih.gov/pubmed/12391317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182532999
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