Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma

The TCL1 protooncogene is overexpressed in many mature B cell lymphomas, especially from AIDS patients. To determine whether aberrant expression promotes B cell transformation, we generated a murine model in which a TCL1 transgene was overexpressed at similar levels in both B and T cells. Strikingly...

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Detalhes bibliográficos
Main Authors: Hoyer, Katrina K., French, Samuel W., Turner, Devin E., Nguyen, Mai T. N., Renard, Mathilde, Malone, Cindy S., Knoetig, Sonja, Qi, Chen-Feng, Su, Thomas T., Cheroutre, Hilde, Wall, Randolph, Rawlings, David J., Morse, Herbert C., Teitell, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137894/
https://ncbi.nlm.nih.gov/pubmed/12381789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212410199
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