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A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

Many drug candidates from marine and terrestrial invertebrates are suspected metabolites of uncultured bacterial symbionts. The antitumor polyketides of the pederin family, isolated from beetles and sponges, are an example. Drug development from such sources is commonly hampered by low yields and th...

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Detaylı Bibliyografya
Yazar: Piel, Jörn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC137826/
https://ncbi.nlm.nih.gov/pubmed/12381784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222481399
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