A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
Many drug candidates from marine and terrestrial invertebrates are suspected metabolites of uncultured bacterial symbionts. The antitumor polyketides of the pederin family, isolated from beetles and sponges, are an example. Drug development from such sources is commonly hampered by low yields and th...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12381784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222481399 |
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