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A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
Many drug candidates from marine and terrestrial invertebrates are suspected metabolites of uncultured bacterial symbionts. The antitumor polyketides of the pederin family, isolated from beetles and sponges, are an example. Drug development from such sources is commonly hampered by low yields and th...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137826/ https://ncbi.nlm.nih.gov/pubmed/12381784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222481399 |
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