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In Swedish families with hereditary prostate cancer, linkage to the HPC1 locus on chromosome 1q24-25 is restricted to families with early-onset prostate cancer.

Prostate cancer clusters in some families, and an estimated 5%-10% of all cases are estimated to result from inheritance of prostate cancer-susceptibility genes. We previously reported evidence of linkage to the 1q24-25 region (HPC1) in 91 North American and Swedish families each with multiple cases...

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Autors principals: Grönberg, H, Smith, J, Emanuelsson, M, Jonsson, B A, Bergh, A, Carpten, J, Isaacs, W, Xu, J, Meyers, D, Trent, J, Damber, J E
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378083/
https://ncbi.nlm.nih.gov/pubmed/10364525
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