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Exploiting excess sharing: a more powerful test of linkage for affected sib pairs than the transmission/disequilibrium test.
The transmission/disequilibrium test (TDT) is a popular, simple, and powerful test of linkage, which can be used to analyze data consisting of transmissions to the affected members of families with any kind pedigree structure, including affected sib pairs (ASPs). Although it is based on the preferen...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2000
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1378049/ https://ncbi.nlm.nih.gov/pubmed/10788332 |
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