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Power comparison of parametric and nonparametric linkage tests in small pedigrees.

When the mode of inheritance of a disease is unknown, the LOD-score method of linkage analysis must take into account uncertainties in model parameters. We have previously proposed a parametric linkage test called "MFLOD," which does not require specification of disease model parameters. I...

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Bibliografiset tiedot
Päätekijät: Sham, P C, Lin, M W, Zhao, J H, Curtis, D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378023/
https://ncbi.nlm.nih.gov/pubmed/10762550
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