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Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development.

Members of the transforming growth factor (TGF)-beta family of cell-signaling molecules have been implicated recently in mammalian left-right (LR) axis development, the process by which vertebrates lateralize unpaired organs (e.g., heart, stomach, and spleen). Two family members, Lefty1 and Lefty2,...

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Bibliographic Details
Main Authors: Kosaki, K, Bassi, M T, Kosaki, R, Lewin, M, Belmont, J, Schauer, G, Casey, B
Format: Artigo
Language:Inglês
Published: 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377788/
https://ncbi.nlm.nih.gov/pubmed/10053005
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