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Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells

We describe a strategy to obtain highly enriched long-term repopulating (LTR) hematopoietic stem cells (HSCs) from bone marrow side-population (SP) cells by using a transgenic reporter gene driven by a stem cell enhancer. To analyze the gene-expression profile of the rare HSC population, we develope...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chen, Chang-Zheng, Li, Min, de Graaf, David, Monti, Stefano, Göttgens, Berthold, Sanchez, Maria-Jose, Lander, Eric S., Golub, Todd R., Green, Anthony R., Lodish, Harvey F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137740/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.202614899
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