Fbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells

Abstract Background The ubiquitin–proteasome system plays important roles in maintaining the self-renewal and differentiation of stem and progenitor cells through highly ordered degradation of cellular proteins. Fbxw11, an E3 ligase, participates in many important biological processes by targeting a...

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Autori principali:	Lina Wang, Yongjun Piao, Dongyue Zhang, Wenli Feng, Chenchen Wang, Xiaoxi Cui, Qian Ren, Xiaofan Zhu, Guoguang Zheng
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-06-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Fbxw11 Hematopoietic stem cell Hematopoietic progenitor cell Single-cell RNA sequencing
Accesso online:	https://doi.org/10.1186/s13287-022-02926-9
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