Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.

Germ-line mutations in DNA mismatch-repair genes impart a markedly elevated cancer risk, often presenting as autosomal dominant hereditary nonpolyposis colorectal cancer (HNPCC). However, there are no pathognomonic features of HNPCC, not all gene carriers have a family history of the disease, and fa...

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Dades bibliogràfiques
Autors principals: Farrington, S M, Lin-Goerke, J, Ling, J, Wang, Y, Burczak, J D, Robbins, D J, Dunlop, M G
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377385/
https://ncbi.nlm.nih.gov/pubmed/9718327
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