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Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins

Leukemic disease can be linked to aberrant gene expression. This often is the result of molecular alterations in transcription factors that lead to their misrouting within the nucleus. The acute myelogenous leukemia-related fusion protein AML1/ETO is a striking example. It originates from a gene rea...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Barseguian, Karina, Lutterbach, Bart, Hiebert, Scott W., Nickerson, Jeffrey, Lian, Jane B., Stein, Janet L., van Wijnen, Andre J., Stein, Gary S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12427969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.242588499
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