Refined genetic mapping of the darier locus to a <1-cM region of chromosome 12q24.1, and construction of a complete, high-resolution P1 artificial chromosome/bacterial artificial chromosome contig of the critical region.

Darier disease (DD) (MIM 124200) is an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and by abnormal keratinization. We present linkage analysis showing, in four families, key recombination events that refine the location of the DD locus on chromosome 12q...

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Hlavní autoři: Monk, S, Sakuntabhai, A, Carter, S A, Bryce, S D, Cox, R, Harrington, L, Levy, E, Ruiz-Perez, V L, Katsantoni, E, Kodvawala, A, Munro, C S, Burge, S, Larrègue, M, Nagy, G, Rees, J L, Lathrop, M, Monaco, A P, Strachan, T, Hovnanian, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377034/
https://ncbi.nlm.nih.gov/pubmed/9529352
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