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An ∼1.2-Mb Bacterial Artificial Chromosome Contig Refines the Genetic and Physical Maps of the Lurcher Locus on Mouse Chromosome 6

Lurcher (Lc) is a semidominant mouse mutant that displays a characteristic ataxia in the heterozygous state beginning in the third postnatal week. This symptom results from a neurodegenerative event in the cerebellum: There is a catastrophic loss of Purkinje cells in the heterozygote animal between...

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Détails bibliographiques
Auteurs principaux: De Jager, Philip L., Zuo, Jian, Heintz, Nathaniel
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC310680/
https://ncbi.nlm.nih.gov/pubmed/9253602
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