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Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

BACKGROUND: Females with the neurological disorder Rett syndrome are heterozygous for mutations in X-linked MECP2 that encodes methyl-CpG binding protein 2 (MeCP2) thought to act as a transcriptional repressor. To identify target genes for MeCP2 modulation, we studied global gene expression in singl...

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Hlavní autoři: Traynor, Jeff, Agarwal, Priyanka, Lazzeroni, Laura, Francke, Uta
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137585/
https://ncbi.nlm.nih.gov/pubmed/12418965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-3-12
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