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Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy

Poly(A(+)) RNA was extracted from the temporal lobe (TL) of medically intractable epileptic patients which underwent surgical TL resection. Injection of this mRNA into Xenopus oocytes led to the expression of ionotropic receptors for γ-aminobutyric acid (GABA), kainate (KAI) and α-amino-3-hydroxy-5-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Palma, Eleonora, Esposito, Vincenzo, Mileo, Anna Maria, Di Gennaro, Giancarlo, Quarato, Pierpaolo, Giangaspero, Felice, Scoppetta, Ciriaco, Onorati, Paolo, Trettel, Flavia, Miledi, Ricardo, Eusebi, Fabrizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137546/
https://ncbi.nlm.nih.gov/pubmed/12409614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232574499
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