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Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy

Poly(A(+)) RNA was extracted from the temporal lobe (TL) of medically intractable epileptic patients which underwent surgical TL resection. Injection of this mRNA into Xenopus oocytes led to the expression of ionotropic receptors for γ-aminobutyric acid (GABA), kainate (KAI) and α-amino-3-hydroxy-5-...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Palma, Eleonora, Esposito, Vincenzo, Mileo, Anna Maria, Di Gennaro, Giancarlo, Quarato, Pierpaolo, Giangaspero, Felice, Scoppetta, Ciriaco, Onorati, Paolo, Trettel, Flavia, Miledi, Ricardo, Eusebi, Fabrizio
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12409614/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232574499
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