In vivo stabilization of the Dnmt1 (cytosine-5)- methyltransferase protein
The Dnmt1o form of the Dnmt1 (cytosine-5)-methyltransferase enzyme is synthesized and stored in the cytoplasm of the oocyte and is used after fertilization to maintain methylation patterns on imprinted genes. After implantation of the blastocyst, Dnmt1o is replaced by the Dnmt1 form, which has an ad...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12397175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.232565599 |
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